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Alcoholic beverages contain ethanol, which is mostly converted into acetaldehyde. The Rochester team found that binge drinking-related levels of acetaldehyde make immune cells called monocyctes more likely to stick to blood vessel walls and cause inflammation that contributes to blood vessel blockage — atherosclerosis.
The study contributes to a growing body of evidence that drinking patterns have as much, or more, impact on cardiovascular disease risk than the total amount of alcohol consumed. The findings also may help efforts to develop new treatments to counter atherosclerosis, which can lead to heart attack and stroke, the researchers said.
“Factors like binge drinking have been linked to increased risk for heart disease, and the newer inflammatory model is beginning to explain how,” study leader John Cullen, an assistant professor in the department of surgery, said in a medical center news release. “One of our experiments found that acetaldehyde, at levels found in the blood after binge drinking, increased the number of monocytes that can adhere to cells lining blood vessels by 700 percent.”
The study was published in the current issue of the journal Atherosclerosis.
Binge drinking means having five or more drinks for men and four or more drinks for women in two hours, according to the U.S. National Institute on Alcohol Abuse and Alcoholism. Some studies have suggested that an irregular pattern of heavy drinking increases the risk of heart attack about two-fold.
An estimated 65 percent of Americans drink alcohol, and 15 percent reporting binge patterns, the researchers said.
Report found a 67.7 percent reduction in illicit drug use over a six month period among people receiving these services The Screening, Brief Intervention, and Referral to Treatment (SBIRT) program can reduce illicit drug use among patients seeking medical care in a wide variety of health care settings such as hospitals, physician offices, and community….
An alarming number of 21-year-olds are participating in a dangerous practice of consuming 21 alcoholic beverages to celebrate reaching legal drinking age, according to a new report by researchers at the University of Missouri. More than a third of men and a quarter of women surveyed at the university who drank alcohol the day they….
The economy is cascading downward at a rate unheard of since the early thirties. Unemployment is rising at a staggering pace, and many flagship industries are closing their doors or cutting production, adding thousands more workers to the unemployment line. President Obama’s stimulus package is designed to stop the economic hemorrhaging and return the nation….
Nurses are to advise patients about their drinking habits as part of a scheme to tackle binge drinking. Patients who return to hospital for treatment after a drink-related injury will receive advice from nurses about their alcohol intake. The assembly government-led scheme will start across Wales in February. The chief nursing officer for Wales said….
When it comes to drinking, it seems as though Americans are fond of taking an alcoholic beverage from time to time. In a Gallup Consumption Habits poll, 63 percent of Americans reported that they drink alcohol, while 37 percent reported they abstain. While alcohol is typically not harmful in moderation, and can actually be beneficial….