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Alcoholic beverages contain ethanol, which is mostly converted into acetaldehyde. The Rochester team found that binge drinking-related levels of acetaldehyde make immune cells called monocyctes more likely to stick to blood vessel walls and cause inflammation that contributes to blood vessel blockage — atherosclerosis.
The study contributes to a growing body of evidence that drinking patterns have as much, or more, impact on cardiovascular disease risk than the total amount of alcohol consumed. The findings also may help efforts to develop new treatments to counter atherosclerosis, which can lead to heart attack and stroke, the researchers said.
“Factors like binge drinking have been linked to increased risk for heart disease, and the newer inflammatory model is beginning to explain how,” study leader John Cullen, an assistant professor in the department of surgery, said in a medical center news release. “One of our experiments found that acetaldehyde, at levels found in the blood after binge drinking, increased the number of monocytes that can adhere to cells lining blood vessels by 700 percent.”
The study was published in the current issue of the journal Atherosclerosis.
Binge drinking means having five or more drinks for men and four or more drinks for women in two hours, according to the U.S. National Institute on Alcohol Abuse and Alcoholism. Some studies have suggested that an irregular pattern of heavy drinking increases the risk of heart attack about two-fold.
An estimated 65 percent of Americans drink alcohol, and 15 percent reporting binge patterns, the researchers said.
Many different factors must be taken into consideration when choosing the right alcohol treatment center. Everyone has different needs and everyone deals with their addiction in a different manner. The longer an addict uses alcohol and the more intense the addiction is typically requires the alcohol treatment to be more intense. Alcohol treatment centers offer….
You may think that private addiction treatment is too expensive, that you can’t afford it or that it can’t possibly be that much better than a similar public treatment program but do you know the true value of private addiction treatment? Do you know that private addiction treatment is your best chance at getting the….
Alcohol-related crime is much higher in communities where more people binge drink, and too many people binge drink in Inverell. That information has come from the initial findings of the Alcohol Action in Rural Communities (AARC) project. Close collaborations with members of the Inverell community and the AARC project have helped reveal that rural NSW….
Drugs can be defined as chemical substances that can have a therapeutic or non- therapeutic effect on the body of the person who consumes them. Among the population of drug abuser, the rate of teenagers is very high, which is the most concerning part of the drug abuse. Teenagers and drug abuse are closely associated….
Alcohol has again outstripped illicit drugs like heroin and ice as the number one reason for admissions at a major Australian rehab service. Problem drinking topped Odyssey House’s 2009 admission list, because 26 per cent of those seeking care over the year named it as their “principal drug of concern”. It was fractionally down from….