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Alcoholic beverages contain ethanol, which is mostly converted into acetaldehyde. The Rochester team found that binge drinking-related levels of acetaldehyde make immune cells called monocyctes more likely to stick to blood vessel walls and cause inflammation that contributes to blood vessel blockage — atherosclerosis.
The study contributes to a growing body of evidence that drinking patterns have as much, or more, impact on cardiovascular disease risk than the total amount of alcohol consumed. The findings also may help efforts to develop new treatments to counter atherosclerosis, which can lead to heart attack and stroke, the researchers said.
“Factors like binge drinking have been linked to increased risk for heart disease, and the newer inflammatory model is beginning to explain how,” study leader John Cullen, an assistant professor in the department of surgery, said in a medical center news release. “One of our experiments found that acetaldehyde, at levels found in the blood after binge drinking, increased the number of monocytes that can adhere to cells lining blood vessels by 700 percent.”
The study was published in the current issue of the journal Atherosclerosis.
Binge drinking means having five or more drinks for men and four or more drinks for women in two hours, according to the U.S. National Institute on Alcohol Abuse and Alcoholism. Some studies have suggested that an irregular pattern of heavy drinking increases the risk of heart attack about two-fold.
An estimated 65 percent of Americans drink alcohol, and 15 percent reporting binge patterns, the researchers said.
Addiction is a term that is used to describe a recurring compulsion by the person that engages him in a particular activity, inspite of the harmful consequences to their health and social life. It is accepted all over that addiction is a disease and a state of psychological dependence on something that can have damaging….
When two mental disorders or illnesses occur at the same time, or in sequence, in the same person, it is known as comorbidity; when these conditions are diagnosed, it is called a dual diagnosis. Mental disorders are defined by the National Institute on Drug Abuse as “A mental condition marked primarily by sufficient disorganization of….
If you picked up a bottle of wine and read on the label “The average British drinker drinks one glass of wine a night”, would it make you think twice before refilling your glass? The Conservatives believe it might – and that public information along those lines is one possible way to reduce binge drinking…..
According to the world renowned Mayo Clinic the definition of Anorexia Nervosa (Anorexia) is: “an eating disorder that causes people to obsess about their weight and the food they eat” (Mayo Definition). Anorexia can cause unrealistic expectations of body type and a distorted view of body image, causing Anorexia suffers to starve themselves trying to….
Are you heading into a treatment program to get help for a drug or alcohol addiction? If you’re already on your way to getting the help you need and you’re trying to figure out what it is that you should (or should not) bring with you to drug or alcohol addiction treatment, consider these items….
