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Alcoholic beverages contain ethanol, which is mostly converted into acetaldehyde. The Rochester team found that binge drinking-related levels of acetaldehyde make immune cells called monocyctes more likely to stick to blood vessel walls and cause inflammation that contributes to blood vessel blockage — atherosclerosis.
The study contributes to a growing body of evidence that drinking patterns have as much, or more, impact on cardiovascular disease risk than the total amount of alcohol consumed. The findings also may help efforts to develop new treatments to counter atherosclerosis, which can lead to heart attack and stroke, the researchers said.
“Factors like binge drinking have been linked to increased risk for heart disease, and the newer inflammatory model is beginning to explain how,” study leader John Cullen, an assistant professor in the department of surgery, said in a medical center news release. “One of our experiments found that acetaldehyde, at levels found in the blood after binge drinking, increased the number of monocytes that can adhere to cells lining blood vessels by 700 percent.”
The study was published in the current issue of the journal Atherosclerosis.
Binge drinking means having five or more drinks for men and four or more drinks for women in two hours, according to the U.S. National Institute on Alcohol Abuse and Alcoholism. Some studies have suggested that an irregular pattern of heavy drinking increases the risk of heart attack about two-fold.
An estimated 65 percent of Americans drink alcohol, and 15 percent reporting binge patterns, the researchers said.
Are you considering alcohol treatment but can decide if luxury alcohol treatment is right for you? Maybe you’ve heard about luxury alcohol treatment before but figure it’s only for celebrities such as those you see on Celebrity Rehab or you might think that luxury alcohol treatment is reserved for high end attorneys, CEOs of major….
To address Madison’s ongoing problem with chronic street alcoholics, a new list could soon be making its way to liquor stores across the city that would prevent those on it from buying alcohol. While city staffers and members of the Alcohol License Review Committee (ALRC) still are working out the details, finding one’s way onto….
Drug use is a serious problem that affects millions of people. Early recognition of the problem can help you to determine whether your loved one needs drug rehab. While you may not want to think about it, without drug rehab, many addicts will continue down a path of destruction that leads them directly to their….
Abuse of prescription pain medications and street drugs, such as heroin and opium has left many recreational users at the mercy of an addiction. Also known as opiate or narcotic drugs, battling this type of addiction requires specialized medical treatment along with ongoing support and guidance. Methadone treatment centers specialize in treating opiate addictions using….
A leading surgeon says breast cancer rates could soar unless young women cut back on binge drinking – and that mammograms are being “oversold”. Dr Trevor Smith said alcohol was among the lifestyle choices that contributed towards New Zealand’s having one of the highest breast cancer rates in the world. He called on the Government….
