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Alcoholic beverages contain ethanol, which is mostly converted into acetaldehyde. The Rochester team found that binge drinking-related levels of acetaldehyde make immune cells called monocyctes more likely to stick to blood vessel walls and cause inflammation that contributes to blood vessel blockage — atherosclerosis.
The study contributes to a growing body of evidence that drinking patterns have as much, or more, impact on cardiovascular disease risk than the total amount of alcohol consumed. The findings also may help efforts to develop new treatments to counter atherosclerosis, which can lead to heart attack and stroke, the researchers said.
“Factors like binge drinking have been linked to increased risk for heart disease, and the newer inflammatory model is beginning to explain how,” study leader John Cullen, an assistant professor in the department of surgery, said in a medical center news release. “One of our experiments found that acetaldehyde, at levels found in the blood after binge drinking, increased the number of monocytes that can adhere to cells lining blood vessels by 700 percent.”
The study was published in the current issue of the journal Atherosclerosis.
Binge drinking means having five or more drinks for men and four or more drinks for women in two hours, according to the U.S. National Institute on Alcohol Abuse and Alcoholism. Some studies have suggested that an irregular pattern of heavy drinking increases the risk of heart attack about two-fold.
An estimated 65 percent of Americans drink alcohol, and 15 percent reporting binge patterns, the researchers said.
A Co-Occurring Disorder is condition wherein mental disorder as well as alcohol problems is faced by an individual side by side. This is a condition that occurs very often. It is important to manage one disorder at a time by treating each one simultaneously to get the best possible outcome. Co-Occurring Disorders are also referred….
Baby boomers made marijuana their ‘gateway’ — and some still can’t let go, a report says — but a younger generation finds prescription drugs are an easier score. It’s been four decades since the dawning of the Age of Aquarius, but aging baby boomers haven’t stopped turning on. The federal government’s National Survey on Drug….
Dr. Charles S. Lieber, who overturned conventional wisdom by demonstrating that alcohol is a toxin that can damage the liver and that alcoholism is a disease that can be treated, died March 1 at his home in Tenafly, N.J. He was 78 and had been battling stomach cancer. Before his work in the 1970s, researchers….
Alcohol treatment is necessary for those who are dependent on and abusing alcohol. Those who become dependent on alcohol are called alcoholics, and they need to be treated formally in a detox or rehab facility. Why is alcohol treatment necessary? Alcohol Withdrawal First and foremost, alcohol withdrawal can be extremely dangerous. As stated by the….
1. Alcohol Withdrawal Can Be Deadly. While some experience mild alcohol withdrawal, others go through “a severe form of alcohol withdrawal called delirium tremens” (NLM). Its symptoms can include seizures, hallucinations, and fever, and a person experiencing it should be taken to the hospital immediately. In treatment, these symptoms can be controlled. 2. It Can….
