A National Directory of Drug Treatment Centers and Alcohol Treatment Centers, Therapists and Specialists. A free, simple directory providing assistance and guidance for those seeking help regarding alcohol addiction, drug addiction, dependency and many other conditions that affect the mind, body and soul.
Call 888-647-0579 to speak with an alcohol or drug abuse counselor.

Who Answers?

Cancer Immunotherapy Shows Long-Term Promise In Lung Cancer

New, long-term results from a clinical trial presented today at the 1st European Lung Cancer Conference jointly organized by the European Society for Medical Oncology (ESMO) and the International Association of the Study of Lung Cancer (IASLC) show that MAGE-A3 ASCI (Antigen-Specific Cancer Immunotherapeutic), an immune-boosting treatment for lung cancer patients, reduces the risk of relapse after surgery — to the same extent as chemotherapy but without the side-effects of chemotherapy.

Prof. Johan Vansteenkiste from University Hospital Gasthuisberg in Belgium described the results after 44-months follow-up from a double-blind, placebo-controlled trial in 182 patients with non-small-cell lung cancer — the most common form of the disease.

After complete surgical resection of the tumor, patients were randomly assigned to receive either placebo injections or injections of MAGE-A3 ASCI administered over 27 months (five given at three-week intervals followed by eight given once every three months).

MAGE-A3 is a tumor-specific antigen, expressed in 35-50% of non-small-cell lung cancer, but not on normal cells.

“The aim is to help the body immune system to recognize the MAGE-A3 antigen and therefore eliminate the cancer cells that express MAGE-A3,” explains Prof. Vansteenkiste. “In other words, it is a kind of treatment method that makes the body immune system specifically attack the lung cancer cells.”

After 44 months, 69 of 182 patients had experienced a recurrence of their cancer, including 57 deaths. Those given the MAGE-A3 injections had longer on average before their cancer recurred, were less likely to have any recurrence, and were less likely to die.

“Surgical resection is the standard treatment for patients with early stage lung cancer, but after complete resection about 50% will relapse and die from their cancer,” says Prof. Vansteenkiste. “Postoperative chemotherapy is able to improve cure rates, but is sometimes poorly tolerated by patients recovering from thoracic surgery. In addition, not all patients are fit to receive chemotherapy. This is why the signal from this phase II randomized study is important: the reduction in risk of postoperative cancer relapse is similar to the one obtained with postoperative chemotherapy, while the side-effects of this new strategy are minimal compared to chemotherapy.”

Most patients only experience mild reactions at the injection site and fever within 24 hours of the injection, he explained. “Therefore, it is suitable for long-term maintenance treatment and for most patients, including older patients or patients in weak physical condition after surgery, allowing them to live a normal life whilst on cancer treatment.” A large Phase III trial of the therapy, named MAGRIT, is now underway.

source: http://www.esmo.org/

More Treatment & Detox Articles

Killer or cure?

Spike in methadone-related deaths has some seeking drug regulation A drug commended years ago for helping to loosen heroin’s deadly grip in Pennsylvania and beyond may now be the region’s No. 1 killer. Coroners say 21 people in Blair, Cambria and Clearfield counties died of accidental methadone overdoses in 2007 – more than the statewide….

Continue reading

Helping Someone With Alcohol or Drug Problem

Alcohol or Drug addiction

If someone confides in you that he or she has a problem with alcohol or other drugs, some ways of dealing with this situation clearly work better than others. You should try to be: Understanding – listen to reasons why he or she uses/ abuses alcohol or other drugs; Firm – explain why you feel….

Continue reading

Center will study effects of alcohol on brain

UNM was given $2.5 million this semester to start one of the nation’s first fetal alcohol research centers. The program is funded by a five-year grant from the National Institute on Alcohol Abuse and Alcoholism. The New Mexico Alcohol Research Center will look at the effects of alcohol on the brain. Dr. Daniel Savage, who….

Continue reading

Fears as more women fall victim to alcohol

Doctors say they are treating “significantly” more women for alcohol-related health problems. The number of women seen at Leicester’s hospitals for serious drink-related conditions has more than doubled since 2004. But doctors fear many more women are gambling with their health by drinking more than they should. Latest figures from the Joseph Rowntree Foundation reveal….

Continue reading

Alcohol craving reduced by drugs

Twin research projects have offered both present and future hope to people suffering from alcohol addiction. US researchers say that epilepsy drug topiramate boosts general health as well as cutting the craving for drink. A UK specialist said the potential side-effects of topiramate still merited caution. A separate project showed that a single injection of….

Continue reading

Where do calls go?

Calls to numbers on a specific treatment center listing will be routed to that treatment center. Calls to any general helpline will be answered or returned by one of the treatment providers listed, each of which is a paid advertiser: ARK Behavioral Health, Recovery Helpline, Alli Addiction Services.

By calling the helpline you agree to the terms of use. We do not receive any commission or fee that is dependent upon which treatment provider a caller chooses. There is no obligation to enter treatment.

I NEED TO TALK TO SOMEONE NOWI NEED TO TALK TO SOMEONE NOW 888-647-0579Response time about 1 min | Response rate 100%
Who Answers?