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Potential Drug Treatment for Alcoholism
A drug currently approved to treat bipolar disorder and schizophrenia may play a role in the treatment of alcoholism. The drug is called aripiprazole (Abilify); researchers say more research is needed, but this first study found the drug helps lessen the euphoric effects of alcohol.
Aripiprazole is a dopamine partial agonist, so it works differently in the body than other dopamine drugs. Study authors say the drug has different effects at different dose levels, so it is important to give the right amount of the drug to achieve the right results.
For the study, researchers recruited 18 social drinkers — nine men and nine women. Each participant completed three sessions in which they were given no medication, or 2.5 milligrams or 10 milligrams of aripiprazole. Then they were given three drinks and researchers measured their breath alcohol concentrations, heart rate, blood pressure, body sway and other subjective effects.
“Findings show that aripiprazole made the drinkers sleepier and they experienced less pleasure from alcohol than they might have without it,” says Henry Kranzler, a professor in the department of psychiatry at the University of Connecticut Health Center. Study authors say this is just preliminary research but one benefit might be that aripiprazole may be more tolerated than other drugs, causing fewer side effects. But researchers say that is still not proven and additional studies need to happen to determine if aripiprazole is a potential treatment for alcoholism.
_________ source: Alcoholism: Clinical & Experimental Research, 2008;32:573-578
ALCOHOL has become the treatment of choice for an unfortunate number of Australian troops left traumatised by their service in East Timor, Afghanistan and Iraq. Taxpayers are now funding rehabilitation and sometimes compensation for their addiction, not to mention attempts to break it, as troops return from mostly dry operations to deal with their problems….
SANTA ANA Orange County spends some $40 million a year on running programs that prevent, treat and rehabilitate drug and alcohol abusers. And this year for the first time, the Health Care Agency published a public report that illustrates who is getting treatment, where they live and their poison of choice. The numbers even reflect….
TORONTO – Laura Adamarczuk was initially blase when asked to complete an online questionnaire to evaluate her drinking habits. The survey was compulsory for residence dons at the University of Western Ontario, but the 21-year-old felt the exercise had minimal value. A student who went out with friends about twice a week was, after all,….
The upcoming holiday season can be particularly stressful if you’ll be spending time with a loved one addicted to alcohol or other drugs. You might feel conflicted about family celebrations; holiday gatherings are supposed to be happy times, but yours don’t look like what you see on television. Should you ignore your loved one’s addiction….
Obama’s decision not to prosecute medical marijuana users and sellers suggests the war on drugs is ending Ships of state tend to change course slowly. Policies set in place over decades, and implemented by large, self-perpetuating bureaucracies and enforcement systems are pretty hard to dismantle. Fundamental change rarely happens overnight. Much of the criticism that….
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