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Potential Drug Treatment for Alcoholism
A drug currently approved to treat bipolar disorder and schizophrenia may play a role in the treatment of alcoholism. The drug is called aripiprazole (Abilify); researchers say more research is needed, but this first study found the drug helps lessen the euphoric effects of alcohol.
Aripiprazole is a dopamine partial agonist, so it works differently in the body than other dopamine drugs. Study authors say the drug has different effects at different dose levels, so it is important to give the right amount of the drug to achieve the right results.
For the study, researchers recruited 18 social drinkers — nine men and nine women. Each participant completed three sessions in which they were given no medication, or 2.5 milligrams or 10 milligrams of aripiprazole. Then they were given three drinks and researchers measured their breath alcohol concentrations, heart rate, blood pressure, body sway and other subjective effects.
“Findings show that aripiprazole made the drinkers sleepier and they experienced less pleasure from alcohol than they might have without it,” says Henry Kranzler, a professor in the department of psychiatry at the University of Connecticut Health Center. Study authors say this is just preliminary research but one benefit might be that aripiprazole may be more tolerated than other drugs, causing fewer side effects. But researchers say that is still not proven and additional studies need to happen to determine if aripiprazole is a potential treatment for alcoholism.
_________ source: Alcoholism: Clinical & Experimental Research, 2008;32:573-578
There is nothing positive about underage drinking. Teenagers sometimes get behind the wheel and drive under the influence which is a big issue. According to studies by the National Crime Prevention Council, automobile crashes related to underage drinking are the leading cause of death for teens. Approximately 36% of traffic deaths of 15- to 20-year-olds….
People are drinking more alcohol by “stealth” because of the stronger drinks on the market, an analysis of consumption in the UK suggests. The amount of alcohol consumed per person has risen by 10% since 2000 – despite drink sales remaining steady. Researchers Mintel said wines and lagers were becoming stronger and people were unaware….
VANCOUVER – Health workers on Vancouver’s Downtown Eastside say they have complained for years about drug addicts being offered kickbacks from pharmacists to fill their methadone prescriptions, a problem they say is getting worse. “We all know about it. The clients know about it, we know about it, but it’s like it’s falling on deaf….
In Dane County, more young people between seventh and 12th grades are abstaining from alcohol than regularly using it, according to a 2005 assessment. Still, the fact that nearly 30 percent of local youth are considered regular drinkers is a cause for concern for many. About 30 people turned out Monday night for the first….
The ancient Egyptian text of the Papyrus Antastasi gave a look into the satirical, yet advanced minds of society. One quote from this text said the following: “Don’t undertake to drink a whole pitcher of beer. Because if you then talk, from your mouth comes nonsense.” Didn’t we learn anything from the ancient Egyptians? Drinking….