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Potential Drug Treatment for Alcoholism
A drug currently approved to treat bipolar disorder and schizophrenia may play a role in the treatment of alcoholism. The drug is called aripiprazole (Abilify); researchers say more research is needed, but this first study found the drug helps lessen the euphoric effects of alcohol.
Aripiprazole is a dopamine partial agonist, so it works differently in the body than other dopamine drugs. Study authors say the drug has different effects at different dose levels, so it is important to give the right amount of the drug to achieve the right results.
For the study, researchers recruited 18 social drinkers — nine men and nine women. Each participant completed three sessions in which they were given no medication, or 2.5 milligrams or 10 milligrams of aripiprazole. Then they were given three drinks and researchers measured their breath alcohol concentrations, heart rate, blood pressure, body sway and other subjective effects.
“Findings show that aripiprazole made the drinkers sleepier and they experienced less pleasure from alcohol than they might have without it,” says Henry Kranzler, a professor in the department of psychiatry at the University of Connecticut Health Center. Study authors say this is just preliminary research but one benefit might be that aripiprazole may be more tolerated than other drugs, causing fewer side effects. But researchers say that is still not proven and additional studies need to happen to determine if aripiprazole is a potential treatment for alcoholism.
_________ source: Alcoholism: Clinical & Experimental Research, 2008;32:573-578
The old adage of “don’t do what I do, do what I say” may very well pertain to older adults when it comes to drinking. A small study of 42 adults, half between the ages of 40 and 75, and half aged 25 to 35, indicated that the older drinkers really may not know when….
Sometimes nothing sounds better after a long, hard day than an ice-cold Dos Equis or a glass of pinot noir. There’s also plenty of research to show that red wine is filled with antioxidants and can increase good cholesterol, while moderate alcohol consumption by men can lead to a decreased risk of heart attack. So….
Heavy drinking adversely affects a person’s performance and perception hours after alcohol has left the body, researchers in Rhode Island said. Researchers at Brown University recruited 95 healthy adults ages 21 to 35 who had reported having a hangover at least one time within the month before the research began. The participants were randomly assigned….
Alcopops. Ever hear of those? Not many people have heard of that term, but they are a drink that is growing in popularity among young people. Alcopop, broken down, is “alcohol” and “pop” (as in soda pop). They are sweet alcoholic beverages that often is fizzy and has had fruit juice added to them. One….
critical surgery Life-saving surgery to prevent repeated severe bleeding from ruptured veins in the esophagus or upper stomach may not induce some patients with alcoholic liver disease to stop drinking alcohol, researchers report. Such a surgical procedure may be necessary to reduce the pressure in the veins of the esophagus and upper stomach among patients….