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Alcoholic beverages contain ethanol, which is mostly converted into acetaldehyde. The Rochester team found that binge drinking-related levels of acetaldehyde make immune cells called monocyctes more likely to stick to blood vessel walls and cause inflammation that contributes to blood vessel blockage — atherosclerosis.
The study contributes to a growing body of evidence that drinking patterns have as much, or more, impact on cardiovascular disease risk than the total amount of alcohol consumed. The findings also may help efforts to develop new treatments to counter atherosclerosis, which can lead to heart attack and stroke, the researchers said.
“Factors like binge drinking have been linked to increased risk for heart disease, and the newer inflammatory model is beginning to explain how,” study leader John Cullen, an assistant professor in the department of surgery, said in a medical center news release. “One of our experiments found that acetaldehyde, at levels found in the blood after binge drinking, increased the number of monocytes that can adhere to cells lining blood vessels by 700 percent.”
The study was published in the current issue of the journal Atherosclerosis.
Binge drinking means having five or more drinks for men and four or more drinks for women in two hours, according to the U.S. National Institute on Alcohol Abuse and Alcoholism. Some studies have suggested that an irregular pattern of heavy drinking increases the risk of heart attack about two-fold.
An estimated 65 percent of Americans drink alcohol, and 15 percent reporting binge patterns, the researchers said.
When you are addicted to prescription medications, private drug treatment can be the most beneficial option to assure your greatest chance of making a full recovery. Unlike traditional treatment centers that may be funded by insurance coverage or state policy, private prescription drug treatment programs are privately funded and this allows for ample resources, better….
In the United States, a standard drink is one that contains about one-half an ounce of pure alcohol. Generally, this amount of pure alcohol is found in 12 ounces of regular beer, 10 ounces of wine cooler, 8 ounces of malt liquor, 5 ounces of wine or one-and-a-half ounces of 80-proof distilled spirits or liquor….
Data gathered by the Substance Abuse and Mental Health Administration show as much as 47 percent of the people discharged from alcohol and drug treatment centers successfully completed their treatment programs in 2006. While different factors, such as types of services provided and the type of problem being treated influence the results, the quality of….
VANCOUVER – Health workers on Vancouver’s Downtown Eastside say they have complained for years about drug addicts being offered kickbacks from pharmacists to fill their methadone prescriptions, a problem they say is getting worse. “We all know about it. The clients know about it, we know about it, but it’s like it’s falling on deaf….
College for many is a four-year opportunity to party without real-world responsibilities. Others are more diligent students with extracurriculars and such, but it’s safe to say that most college students have been stung by the short-term effects of one-too-many shots of vodka or Solo cups full of mysterious “Jungle Juice.” It’s a familiar scene in….