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Alcoholic beverages contain ethanol, which is mostly converted into acetaldehyde. The Rochester team found that binge drinking-related levels of acetaldehyde make immune cells called monocyctes more likely to stick to blood vessel walls and cause inflammation that contributes to blood vessel blockage — atherosclerosis.
The study contributes to a growing body of evidence that drinking patterns have as much, or more, impact on cardiovascular disease risk than the total amount of alcohol consumed. The findings also may help efforts to develop new treatments to counter atherosclerosis, which can lead to heart attack and stroke, the researchers said.
“Factors like binge drinking have been linked to increased risk for heart disease, and the newer inflammatory model is beginning to explain how,” study leader John Cullen, an assistant professor in the department of surgery, said in a medical center news release. “One of our experiments found that acetaldehyde, at levels found in the blood after binge drinking, increased the number of monocytes that can adhere to cells lining blood vessels by 700 percent.”
The study was published in the current issue of the journal Atherosclerosis.
Binge drinking means having five or more drinks for men and four or more drinks for women in two hours, according to the U.S. National Institute on Alcohol Abuse and Alcoholism. Some studies have suggested that an irregular pattern of heavy drinking increases the risk of heart attack about two-fold.
An estimated 65 percent of Americans drink alcohol, and 15 percent reporting binge patterns, the researchers said.
In Southern California alone, there are hundreds of “Recovery Treatment Programs” or “Drug and Alcohol Rehabs.” Southern California has been ranked the second most popular place in the United States for individuals to seek help, for their drug and alcohol addictions. You have a choice when it comes to women’s drug and alcohol treatment programs….
The right of Spanish youths to party in the streets is in question. The “botellon” phenomenon, literally “big bottle,” attracts gatherings of youths to drink in parks and squares. People bring their own drinks: soda to mix with gin, vodka or whisky, and wine to make “calimocho,” a blend of coke and wine. Some botellones….
Call it the chicken-and-egg debate of the addiction world: Cocaine addicts are known for being frenetic, but which came first, the behavior or the habit? New research indicates that, at least in rats, it’s the behavior that begets addiction. What’s more, the study has pinpointed the character trait–impulsiveness–that is responsible for developing true drug dependence…..
Regardless of the type of drug involved, addictive drugs all exert certain effects that increase the likelihood of ongoing drug use. Also known as psychoactive agents, these drugs are able to cross the blood-brain barrier, which gives them easy access to the brain’s workings. According to the National Institute on Drug Abuse, drug addiction creates….
Many veterans experience the ravages of war and combat first-hand. Most anyone put through these types of experiences carries some form of emotional and even psychological scarring. Couple this with the wide range of physical injuries that take place, and it is little wonder drug addiction affects so many veterans in one form or another…..